Symbicort vs. Alternatives: Which Asthma Inhaler Is Right for You?

Asthma Inhaler Decision Calculator

This calculator helps you select the most appropriate asthma inhaler based on your personal needs and preferences. Use the inputs below to determine which inhaler may work best for you, then consult your healthcare provider for personalized medical advice.

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How It Works

MDI

Best for patients with limited inspiratory flow or coordination issues

DPI

Requires stronger inhalation; better for patients with good respiratory function

Once Daily

Simpler dosing for better adherence

Twice Daily

More frequent monitoring for better symptom control

Your Recommended Inhaler

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Trying to choose the right inhaler can feel like a maze of brand names, dosages, and device types. You might have heard about Symbicort alternatives and wonder whether they really offer something better for your asthma or COPD. This guide cuts through the jargon, compares the most common options, and helps you decide which inhaler fits your daily routine.

Key Takeaways

  • Symbicort combines a steroid (budesonide) with a long‑acting bronchodilator (formoterol) in a metered‑dose inhaler.
  • Alternatives like Advair Diskus, Breo Ellipta, and Dulera use different steroid/bronchodilator pairings and delivery devices.
  • Price, dosing frequency, and inhaler technique are the three biggest factors that swing the decision.
  • If you need once‑daily dosing, Breo Ellipta and Arnuity Ellipta are strong candidates.
  • Always check with your prescriber before switching - small differences can affect control and side‑effects.

What Is Symbicort?

Symbicort is a combination inhaler that contains the inhaled corticosteroid budesonide and the long‑acting beta‑agonist (LABA) formoterol. It is delivered via a metered‑dose inhaler (MDI) and is approved for asthma and chronic obstructive pulmonary disease (COPD) maintenance therapy.

How Budesonide and Formoterol Work Together

Budesonide reduces airway inflammation, cutting down swelling and mucus production. Formoterol relaxes smooth muscle in the airways, keeping them open for up to 12 hours. The fast onset of formoterol also lets patients use the same inhaler as a rescue option in emergencies, although guidelines advise a separate short‑acting bronchodilator for acute symptoms.

When Doctors Prescribe Symbicort

Typical candidates include adults with moderate‑to‑severe asthma who need both anti‑inflammatory control and bronchodilation, and some COPD patients who experience frequent exacerbations. The usual dose is two inhalations twice a day, but doctors may adjust based on symptom control and side‑effects.

Split view showing mist from an MDI inhaler and powder cloud from a DPI inhaler.

Common Alternatives to Symbicort

Below are the most frequently mentioned alternatives, each with its own steroid‑LABA pairing and delivery device.

Advair Diskus (fluticasone propionate / salmeterol) is delivered as a dry‑powder inhaler (DPI) and is approved for asthma and COPD. It requires a deep, fast inhalation to disperse the powder.

Breo Ellipta (fluticasone furoate / vilanterol) comes in a once‑daily DPI. Its ultra‑low‑dose steroid is designed for patients who prefer a single daily inhalation.

Dulera (mometasone furoate / formoterol) uses an MDI similar to Symbicort but with a different steroid. It is positioned for adolescents and adults with moderate asthma.

Pulmicort (budesonide) is a steroid‑only inhaler, available as a DPI or nebulizer solution. It’s often added to a LABA inhaler when a separate steroid is preferred.

Arnuity Ellipta (fluticasone furoate) is a steroid‑only once‑daily DPI, useful for patients who already use a separate LABA inhaler.

Side‑Effect Profile Comparison

All inhaled steroids can cause oral thrush, hoarseness, and, in rare cases, systemic effects like lowered bone density. LABAs may lead to tremor, palpitations, or headache. The main differentiators are:

  • Device type: MDIs (Symbicort, Dulera) are easier for patients with limited inspiratory flow, while DPIs (Advair Diskus, Breo Ellipta) need a strong inhalation breath.
  • Dose frequency: Twice‑daily (Symbicort, Advair) versus once‑daily (Breo, Arnuity).
  • Cost: Generic budesonide/formoterol inhalers have become more affordable in the UK, while branded DPIs remain pricier.

Price Snapshot (UK 2025)

Average monthly cost of each inhaler (including NHS prescription fee)
Inhaler Active Ingredients Device Dosing Frequency Monthly Cost (£)
Symbicort Budesonide 160µg / Formoterol 4.5µg per actuation MDI 2× daily £28‑£34
Advair Diskus Fluticasone 100µg / Salmeterol 50µg per inhalation DPI 2× daily £32‑£38
Breo Ellipta Fluticasone furoate 100µg / Vilanterol 25µg per inhalation DPI Once daily £38‑£44
Dulera Mometasone furoate 100µg / Formoterol 5µg per actuation MDI 2× daily £30‑£36
Pulmicort DPI Budesonide 200µg per inhalation DPI 2× daily £22‑£28
Arnuity Ellipta Fluticasone furoate 200µg per inhalation DPI Once daily £35‑£41

Choosing the Right Inhaler: Decision Criteria

  1. Inhalation technique: If you struggle with a deep breath, an MDI (Symbicort, Dulera) is safer.
  2. Dosing convenience: For a busy lifestyle, once‑daily DPIs (Breo, Arnuity) cut down on forgetting doses.
  3. Cost sensitivity: Generic budesonide/formoterol options are usually cheaper than branded DPIs.
  4. Side‑effect tolerance: Some patients report less throat irritation with fluticasone‑based inhalers.
  5. Specific disease profile: COPD patients who need stronger bronchodilation may benefit from the higher LABA potency in Salmeterol (Advair).
Hand holding a checklist next to several inhalers with icons for dose, cost, and technique.

Pros & Cons at a Glance

Inhaler Pros Cons
Symbicort Fast‑acting LABA, good for rescue; MDI works with low inspiratory flow. Twice‑daily dosing, higher price than generic budesonide alone.
Advair Diskus Well‑studied; combines two proven agents. Requires strong inhalation; twice daily.
Breo Ellipta Once‑daily convenience; very low steroid dose. More expensive; DPI may be hard for young children.
Dulera Formoterol gives rapid onset; MDI. Less data than Advair; slightly higher cost.
Pulmicort Steroid‑only, good for step‑down therapy. No LABA - you’ll need a separate bronchodilator.
Arnuity Ellipta Once‑daily high‑potency steroid. No LABA component; higher price.

Tips for Getting the Most Out of Your Inhaler

  • Shake MDI inhalers (like Symbicort and Dulera) for at least 5 seconds before each use.
  • Exhale fully, then inhale slowly and deeply for DPIs (Advair, Breo, Arnuity).
  • Hold your breath for about 10 seconds after inhalation to let the medication settle.
  • Rinse your mouth with water and spit after each steroid dose to prevent thrush.
  • Keep the inhaler dry and store it at room temperature; avoid extreme heat.

When to Talk to Your Healthcare Provider

If you notice worsening symptoms despite regular use, experience frequent oral thrush, or have difficulty mastering the inhaler technique, schedule a review. A small adjustment-switching from a twice‑daily MDI to a once‑daily DPI-can dramatically improve adherence and control.

Frequently Asked Questions

Can I use Symbicort as a rescue inhaler?

Formoterol in Symbicort works faster than many LABAs, so many clinicians allow a single actuation for sudden breathlessness. However, a short‑acting bronchodilator like salbutamol is still the preferred rescue medication for most patients.

Is a DPI better than an MDI for severe asthma?

DPIs need a strong inhalation flow, which can be difficult during an asthma attack. MDIs deliver medication regardless of flow, making them safer for severe or uncontrolled asthma.

How does the cost of Symbicort compare to generic alternatives?

In the UK, a generic budesonide/formoterol inhaler costs around £22‑£28 per month, while the branded Symbicort sits at £28‑£34. The price gap narrows when the NHS provides the prescription pre‑payment certificate.

Do I need a spacer with Symbicort?

A spacer can help if you have coordination issues, but it isn’t required for most adults. Using a spacer may reduce oropharyngeal deposition and lower the risk of thrush.

Can I switch from Advair Diskus to Symbicort without a doctor’s approval?

No. Both drugs contain different steroids and LABAs, and the dosing schedule changes. Switching without medical guidance can lead to loss of control or increased side‑effects.