Corticosteroids can cause serious mood and behavioral changes, including psychosis, especially at high doses. Learn the signs, risks, and what to do if you or a loved one experiences these side effects.
MoreSteroid Side Effects: What You Need to Know Before Taking Them
When doctors prescribe steroids, synthetic versions of hormones your body naturally makes to control inflammation and immune responses. Also known as corticosteroids, they’re powerful tools—but they don’t come without trade-offs. Many people take them for conditions like asthma, arthritis, or skin rashes, and they work fast. But if you’ve ever felt bloated, moody, or had trouble sleeping after starting a steroid course, you’re not alone. These aren’t random side effects—they’re predictable, well-documented reactions to how steroids interact with your metabolism, immune system, and even your brain.
The most common steroid side effects, include weight gain, fluid retention, and elevated blood sugar. Also known as steroid-induced diabetes, this happens because steroids make your liver release more glucose and block insulin from doing its job. For people with diabetes or prediabetes, even a short course can spike blood sugar levels dangerously. Long-term use can lead to thinning skin, easy bruising, muscle weakness, and bone loss. And while you might hear about mood swings or insomnia, fewer people talk about how steroids can suppress your immune system enough to make a simple cold turn into something serious.
Not all steroids are the same. prednisone, a widely used oral corticosteroid. Also known as Deltasone, it’s often the go-to for inflammation, but it’s also one of the most likely to cause systemic side effects. Topical steroids, like creams for eczema, have fewer risks because they’re absorbed in smaller amounts—but misuse, especially on kids or large skin areas, can still lead to problems. Even eye drops with steroids can raise eye pressure and cause glaucoma if used too long. The key isn’t avoiding steroids altogether—it’s using them wisely, for the shortest time possible, and knowing when to ask for alternatives.
That’s where the posts below come in. You’ll find real-world guides on how to spot dangerous steroid use, what safer options exist for managing inflammation, how to monitor blood sugar when you’re on them, and when to push back if your doctor doesn’t mention the risks. Some posts break down how to tell if a generic version is just as safe. Others show how to manage nausea or other side effects without stopping treatment. There’s even a direct comparison between prednisone and newer alternatives that don’t wreck your bones or blood sugar. This isn’t fear-mongering—it’s practical info from people who’ve been there, and from experts who’ve studied the data. Whether you’re just starting a steroid course or have been on one for months, you’ll find something here that helps you take control.